Scientists have successfully tested some germline gene therapy involving replacing genetic mutations in mitochondrial DNA of a mother’s egg to produce a disease-free, or genetically proper, egg.
“In theory, this research has demonstrated it is possible to use this therapy in mothers carrying mitochondrial DNA diseases so that we can prevent those diseases from being passed on to their offspring,” said Shoukhrat Mitalipov, of Oregon Health and Science University in Beaverton, Oregon.
While conventional gene therapy has been tried in humans for over 20 years, germline gene therapy – involving mitochondrial DNA – is new and means that the changes would be passed on to the next generation.
Read more about this new study HERE. This is exciting news in the world of mitochondrial disease!